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	Provedor de dados Anais da ABC (AABC) (1) J. Venom. Anim. Toxins incl. Trop. Dis. (1) Autor ANDRICOPULO,ADRIANO D. (1) Chippaux,Jean-Philippe (1) FERREIRA,LEONARDO G. (1) Habib,Abdulrazaq G. (1) Massougbodji,Achille (1) OLIVA,GLAUCIUS (1) Mais... Palavra-chave Neglected tropical diseases (2) Antivenom (1) Cancer (1) Control (1) Envenomation (1) Ligand-based drug design (1) Medicinal chemistry (1) Snakebite (1) Structure-based drug design (1) Sub-Saharan Africa (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2019 (1) 2018 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última From Medicinal Chemistry to Human Health: Current Approaches to Drug Discovery for Cancer and Neglected Tropical Diseases Anais da ABC (AABC) FERREIRA,LEONARDO G.; OLIVA,GLAUCIUS; ANDRICOPULO,ADRIANO D.. ABSTRACT Scientific and technological breakthroughs have compelled the current players in drug discovery to increasingly incorporate knowledge-based approaches. This evolving paradigm, which has its roots attached to the recent advances in medicinal chemistry, molecular and structural biology, has unprecedentedly demanded the development of up-to-date computational approaches, such as bio- and chemo-informatics. These tools have been pivotal to catalyzing the ever-increasing amount of data generated by the molecular sciences, and to converting the data into insightful guidelines for use in the research pipeline. As a result, ligand- and structure-based drug design have emerged as key pathways to address the pharmaceutical industry’s striking demands for... Tipo: Info:eu-repo/semantics/article Palavras-chave: Medicinal chemistry; Ligand-based drug design; Structure-based drug design; Cancer; Neglected tropical diseases. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000200645 The WHO strategy for prevention and control of snakebite envenoming: a sub-Saharan Africa plan J. Venom. Anim. Toxins incl. Trop. Dis. Chippaux,Jean-Philippe; Massougbodji,Achille; Habib,Abdulrazaq G.. Abstract Snakebite is a critical public health issue in tropical countries, particularly in Africa, where 20% of snakebites globally occur. In 2017, the WHO added snakebite envenoming to the category A of neglected tropical diseases. In 2019, thanks to broad institutional and international NGO support, including strong mobilization of African experts and governments, WHO launched a strategy for prevention and control of snakebite envenoming with more ambitious goals. In sub-Saharan Africa, accessibility of antivenoms and symptomatic, adjuvant or replacement therapy is a priority. Several antivenoms are available but their evaluation has not been properly carried out and they remain expensive. To date, there are no manufacturers of antivenom in sub-Saharan... Tipo: Info:eu-repo/semantics/other Palavras-chave: Snakebite; Envenomation; Antivenom; Sub-Saharan Africa; Neglected tropical diseases; Control. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100101 Registros recuperados: 2 Primeira ... 1 ... Última

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